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Phase III Trial of Lomustine-Temozolomide Combination Therapy Versus Standard Temozolomide in Patients with Methylated MGMT Promoter Glioblastoma.
Protocol: 142202Principal Investigator:
- Vincent Yeung (Rutgers Cancer Institute of New Jersey-University Hospital)
Applicable Disease Sites: Brain and Nervous System -
A Phase 2 Study of Dabrafenib with Trametinib after Local Irradiation in Newly-Diagnosed BRAFV600-Mutant High-Grade Glioma (HGG).
Protocol: 112302Principal Investigator:
- Teena Bhatla (Newark Beth Israel Medical Center)
Applicable Disease Sites: Brain and Nervous System -
A Phase 3 Randomized, Placebo-Controlled Trial Evaluating Memantine for Neurocognitive Protection in Children Undergoing Cranial Radiotherapy as Part of Treatment for Primary Central Nervous System Tumors.
Protocol: 112306Principal Investigator:
- Peter Cole M.D. (Rutgers University)
Applicable Disease Sites: Brain and Nervous System -
Individual Patient Expanded Access for treatment of IDH-1 or IDH2-mutated glioma.
Protocol: 142401Principal Investigator:
- Vincent Yeung (Rutgers Cancer Institute of New Jersey-University Hospital)
Applicable Disease Sites: Brain and Nervous System
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